Symbol
Name
ID

Cdkn2a
cyclin dependent kinase inhibitor 2A
MGI:104738

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes

Increased circulating IgA level

Increased circulating IgG level

Decreased circulating antibody level

Paraproteinemia

Abnormal bleeding

Anemia

Acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemias

Acute myeloid leukemia

Abnormality of coagulation

Thrombocytopenia

Lymphoma

Multiple myeloma

Myelodysplasia

Splenomegaly

Hepatosplenomegaly

Disease(s) Associated with CDKN2A

acute lymphoblastic leukemia

acute myeloid leukemia

multiple myeloma

myelodysplastic syndrome

neuroblastoma

pancreatic cancer

Mouse Phenotypes		increased splenocyte proliferation	increased thymus weight	thymus hyperplasia	increased double-positive T cell number	extramedullary hematopoiesis	increased CD4-positive, alpha-beta T cell number	increased CD8-positive, alpha-beta T cell number	abnormal spleen morphology	abnormal spleen red pulp morphology	increased spleen white pulp amount
Availability	Mouse Genotype	increased splenocyte proliferation	increased thymus weight	thymus hyperplasia	increased double-positive T cell number	extramedullary hematopoiesis	increased CD4-positive, alpha-beta T cell number	increased CD8-positive, alpha-beta T cell number	abnormal spleen morphology	abnormal spleen red pulp morphology	increased spleen white pulp amount
	Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp
	Cdkn2a^tm2.1Rdp/Cdkn2a^tm2.1Rdp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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